用核心种质掖478和铁7922组配成基础材料F₂代与早熟种质6314为原始材料，连续自交多代，育成中熟、高配合力、抗病性强和综合农艺性状好的玉米自交系D22。用其组配的杂交种早熟、抗逆性强、适应性广，成为我国玉米育种中重要的中熟种质资源之一。

D22 inbred line was bred by F₂ generation of the inbred line with high-combining ability collection creative Ye478 and collection creative Tie 7922 crossed early germplasm 6314. D22 inbred line and the hybrid maize varieties combined with it are extensively in all over China.